Why Diet Soda Could Actually Prevent You From Losing Weight

Why Diet Soda Could Actually Prevent You From Losing Weight

Why Diet Soda Could Actually Prevent You From Losing Weight

Reaching for a diet soda may actually hinder weight loss attempts, a new analyze done in mouse suggests.

In experiments, researchers found that the artificial sweetener aspartame, which is found in some diet drinks, may contribute to the development of a condition called “metabolic disorder, ” which involves a cluster of symptoms, including high blood pressure, high cholesterol levels and a large waist sizing. People with metabolic syndrome face an increased risk of heart disease, stroke and diabetes.

The researchers received how aspartame could be linked with metabolic disorder: Aspartame may stop a key gut enzyme from performing its work in breaking down fat during digestion.[ 7 Biggest Diet Myths]

“This is the novel mechanistic insight, ” and it may explain why diet beverages can be ineffective at helping people to lose weight, Dr. Richard Hodin, senior writer of the study and a professor of surgery at Harvard Medical School, told Live Science.

The study included three separate experiments. In the first, researchers added the gut enzyme to solutions of diet soda and regular soda. They found that the activity of the enzyme was significantly lower in the solutions of diet soda as compared to the solutions of regular soda.

Normally, the enzyme — intestinal alkaline phosphatase, or IAP — works in the bowels to break down cholesterol and fatty acids. Previous surveys by the researchers showed that levels of IAP may be linked with people’s risk of obesity, diabetes and metabolic syndrome.

In the second experiment, researchers looked at the effects of aspartame in the small intestines of male mouse. They injected either a solution containing aspartame or a placebo solution of salt water into the small intestines of the mouse, and then measured the same gut enzyme’s activity. They found that 3 hours later, the enzyme’s activity was 50 percent lower in mouse that were injected with the aspartame solution as compared to the mouse injected with the salt water.

In the final experiment, the researchers looked at four groups of male mice over a period of 18 weeks: The mice were all allowed to eat as much food as they wanted, but working groups “ve been given” normal food and two groups “ve been given” high-fat food. Within each division, one group received water to drink that contained aspartame, while the other received regular water to drink.[ 5 Experts Answer: Is Diet Soda Bad for You ?]

At the end of this experimentation, the researchers found that the mouse given the high-fat food and the aspartame-infused water gained more weight than the mouse fed a high-fat food and the regular water.

However, the aspartame did not seem to make a difference for the mouse on the normal diet: There was no change in weight gain between different groups given aspartame water and the group given regular water.

In addition to the difference in weight gain among the mouse on the high-fat diet, the researchers also found that the mice on both diets that drank the aspartame-infused water had significantly higher levels of glucose fanaticism than mice that drank the regular water. Glucose intolerance is a condition in which the body has difficulty employing the glucose in the bloodstream, leading to higher levels of glucose in the blood, and which may lead to diabetes.

Also, both of the groups of mouse that drank the aspartame-infused water presented increased markers of inflammation, which previously has been linked to the development of the metabolic disorder, the researchers said.

The new outcomes should be confirmed in experiments with a larger sample size, the researchers told. In addition, merely male mice were used in the experimentation, which is significant because males and mouse tend to react differently to dietary changes; for example, male mouse tend to have higher levels of diet-induced rednes, and female mice have better insulin sensitivity.

It remains unclear whether the findings may apply to people.

The effects of aspartame may be more complicated in humans, due to a “number of factors related to human behaviour, ” Hodin told Live Science. However, he told, all else being equal, “diet drinks are likely not a great alternative to sugary sodas. Water is probably better.”

Original on Live Science.

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Why Diet Soda Could Actually Prevent You From Losing Weight
Why Diet Soda Could Actually Prevent You From Losing Weight
Why Diet Soda Could Actually Prevent You From Losing Weight
Why Diet Soda Could Actually Prevent You From Losing Weight
Why Diet Soda Could Actually Prevent You From Losing Weight

Why Diet Soda Could Actually Prevent You From Losing Weight

Why Diet Soda Could Actually Prevent You From Losing Weight

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